Διάκριση παραγωγικών και υποστρέψιμων βλαβών

? ?????????????? ??????? ?????? ???? ???????? ???? ??????? ??? ?????????? ???????? ??? ???????? ?? ?????????? ??????????? ??? ???????? ??????, ??????? ??? ?????????????? ??? ?? ????????????? ??? ???? ???????? ????????? ??? ???????.

???? ?????? ????????, ???? ? ?????? ??? ??????? ?? ??? ?????? ??? ??????? ???????????? ?? 1988 ?????? ?????, CIN3 ???? ?????????? ????????? ??? ???? ?????????????? ?? ???????? ??????? 25-29 ???? (????? 5.3). ???? ????? ?????? ??? ? ???????? ????? ??? ????????? ??????? ??????????? HPV ??????? (????? 5.4) ??????????? ?? ?????????? ?????? LSIL, ??? ?????? ??????????? ?????????, ??? HSIL, ? ????? ?????????? ???? ??????? ???????? ?? ????????? ???????, ??? ????? ????? ??? ??? ????????????.

??? ? ????????????? ??????? ??????? ???????? ??? ???????? ????? ??????? ?? ???????? ?????????? ??? 30 ????, ??????????? ??? ??????????????? ???????? ????? ??????? ?? ??????? ?? ???????? ??????? 25-29 ???? ?? ???? ???????????? ?????????? (Castanon et al. 2013).

 

Figure 5.3. Data taken from Office for National Statistics records for England (1992-2013) and England and Wales (1972-1982) Data available from  http://www.ons.gov.uk/ons/rel/vsob1/cancer-statistics-registrations--england--series-mb1-/index.html

 

HSIL ??? LSIL ?? ???????????? ??????????

  • ??? ?????????? ??? ???? ?????????? ?????? ????????? ??????? ??? ?????? ????????, CIN2-3 ????? ??????????? ????? ?? ???????? ??????? 25-29 ????
  • ???????? ???????? ???? ??? ?????? ????? ??????? ?????? ?? ?????? ?? ???????? ??????? 25-29 ????
  • LSIL ??? HPV ??????? ??????? ????????? ?? ???????? ??????? ?????????? ??? 30 ????
  • ? ????????????? ???????? ?????? HSIL ??? LSIL ????? ?? ?????? ??? ????????? ??????

 

??????? ????-????????? ??? ???????????? ??????

?? Wilson & Jungner (1968) ??????????? ?? ?????? ???????? ??? ????-????????? «???????» ?????????? (????? 5.2), ?? ????? ???? ????????? ??? ????? ??? ???????? ?? ??? ?????? ??? ???????? ??? ????????. ??? ??????????? ?????????? ? ??????? ??? LSIL ???? ?? ????? ? ?????? ????????????? ???????????? ??????? ???? ???? ??? HSIL. ??? ??????????, ??? ?????? ???????? (???????? 2013-2014) 1.8% ??? ??????? ?????????????? ????????????? ??????????? ?? ?????? ?????????? (????????? ?? LSIL) ? ?????? (5.3%) ???????????? ?? 1.3% ??????-?????? ?????????? (????????? ?? HSIL) ? ??????? (HSCIC 2014).  ????????, ??????? ??? HPV ??????? ???????? ?? ??????????? ???????????? (?? ???????) ???? ?????? ????? ????? ????????? (????? 5.4, ??? ???? Bruni et al. 2010).

????? 5.4. ??????? ???????? HPV+ ?? ??????????? ???????????? ?? ???????????? ????????? ??????(????? 2 ??? ???? Bruni et al. 2010)

 

???????? ???????????? ???????????? ??? ??????? ??????

  • ASC-US ??? LSIL ????? ????????? ?? ????? ?? HSIL
  • ??????? HPV ??????? ???????? ?? ??????????? ???????????? ????? ????? ????????? ?? ????? ?? ASC-US ?? ?????? ????????

 

X